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High-Efficiency Aseptic Filling Line: Automated Solutions for Pharma, Biotech & Cosmetics

Categories Vial Filling Machine
Brand Name: Lingyao
Model Number: LYKXGF2-30
Certification: CE, ISO, GMP
Place of Origin: China
MOQ: 1 unit
Price: 200,000-400,000USD per piece
Payment Terms: D/A,D/P,T/T,Western Union
Supply Ability: 3 pcs per 6 months
Delivery Time: 180 work days normally
Packaging Details: carton, wood carton, pallets
Machine Name: Vial Filling Line
Scalability & Flexibility: 2-30ml vials
Output Capacity: 6000-26000 BPH
Function: Vials Washing, Sterilization, Filling, Plugging, Capping
Vials Material: Glass
Precision & Accuracy: High-precision filling +/-1%
Sterilization Capability: Integrated sterilization processes(ultrasonic cleaning, dry heat sterilization)
After-sales Service & Technical Support: 1-2 years guarantee maintenance, free spare parts available, and trouble assistance to minimize downtime
Energy Efficiency: water, energy aligned with sustainability goals
Data Integrity & Traceability: 21 CFR Part 11
CIP/SIP: Yes
LAF: Yes
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High-Efficiency Aseptic Filling Line: Automated Solutions for Pharma, Biotech & Cosmetics

High-Efficiency Aseptic Filling Line: Automated Solutions for Pharma, Biotech & Cosmetics


Process Logic: Advanced Aseptic Manufacturing

This system goes beyond basic liquid filling by integrating a highly controlled, step-by-step process logic to protect sensitive formulations:

  1. Thermal Stabilization: Formulations enter the system through integrated cooling jackets, maintaining strict temperature control. This is vital for heat-sensitive fillers like mRNA vaccines and collagen-based cosmetics.

  2. Oxidation Prevention: Before the liquid is dispensed, active nitrogen purging technology displaces oxygen within the vial. This protects oxygen-sensitive compounds, such as peptide-based formulations and volatile essential oils, from degradation.

  3. Precision Servo-Dosing: High-viscosity biotech solutions and lightweight cosmetic essences are accurately dispensed using servo-driven pumps. This mechanical design ensures exceptional dosage consistency (up to ±0.5% accuracy), a non-negotiable factor for oncology s and hormone therapies.

  4. Lyophilization Integration: For biologics requiring ultra-low temperature handling, the line seamlessly integrates with upstream freeze-drying (lyophilization) equipment, maintaining an unbroken aseptic chain.

  5. Secure Sealing & Output: Vials are stoppered and capped with a >99% pass rate, ensuring absolute sterility before exiting the cleanroom environment.


Application Scenarios

The modular design of this automated vial filler allows facilities to pivot quickly between distinct industry requirements:

  • Sterile & Vaccine Production: Engineered to comply with WHO and FDA regulations, ensuring absolute sterility for injectable antibiotics, insulin, and sensitive mRNA vaccines.

  • Biotechnology: Easily manages the high viscosity of stem cell serums and biologic reagents, supporting rapid changeovers between single-dose vials and larger bulk reagent bottles.

  • Premium Cosmetics: The ideal cosmetic filling machine for high-value skincare products. It flawlessly processes cosmetic essences, serums, and essential oils without cross-contamination.


Why Choose This Specific Solution?

When evaluating capital equipment, this aseptic filling line delivers distinct operational and strategic advantages:

  • Scalable Throughput: Choose the precise configuration that matches your market demand, scaling effortlessly from 6,000 pieces per hour for R&D batches up to 26,000 vials per hour for large-scale commercial launches.

  • Reduced Operational Overhead: An optimized, energy-saving design reduces power consumption by up to 30% compared to traditional legacy systems.

  • Environmental Resilience: Constructed from heavy-duty 316L stainless steel, this machinery resists corrosion from aggressive cleaning agents and performs reliably in high-humidity regions like Southeast Asia and the Middle East.

  • Accelerated Market Entry: Equipment comes with pre-validated documentation, drastically speeding up regulatory approvals in strict markets such as the EU, GCC, and ASEAN.

  • Global Reliability: Backed by 24/7 technical support and global service hubs, ensuring rapid trouble and immediate spare parts availability.

Benchmarking: Our Solution vs. Industry Standards

Feature Standard Filling Equipment Our High-Efficiency Aseptic Line
Dosing Technology Pneumatic pumps (±2% accuracy) Servo-driven pumps achieving up to ±0.5% precision.
Atmospheric Control Ambient air exposure Nitrogen purging for zero-oxidation of sensitive APIs.
Temperature Control Requires external facility cooling Integrated cooling jackets for direct thermal management.
Energy Consumption High constant draw 30% reduced power usage via modular configuration.
Regulatory Validation Requires extensive localized testing Pre-validated documentation for accelerated EU/GCC/ASEAN approval.


Technical Specifications Overview

Note: Performance metrics vary based on the specific model configuration selected for your facility.

Specification Model LYQCL-80 Model LYQCL-100 Model LYQCL-120
Adaptive Spec 2-30ml Standard Vials 2-30ml Standard Vials 2-30ml Standard Vials
Capacity 6,000 - 12,000 pcs/hr 6,000 - 18,000 pcs/hr 6,000 - 26,000 pcs/hr
Total Power ~90kW (380v 50Hz) ~93kW (380v 50Hz) ~110kW (380v 50Hz)
Dimensions (L x W x H) 12600 X 2260 X 2445 mm 12600 X 2260 X 2445 mm 13200 X 2260 X 2445 mm
Clarity > 99% > 99% > 99%
Breakage Rate < 0.5% < 0.5% < 0.5%
Standard Filling Tolerance ≤ 1.5% ≤ 1.5% ≤ 1.5%
Stoppering Pass Rate > 99% > 99% > 99%
Capping Pass Rate > 99% > 99% > 99%
Fresh Water Consumption 0.6 - 1.0 m³/hr (0.2-0.4 Mpa) 0.6 - 1.0 m³/hr (0.2-0.4 Mpa) 0.6 - 1.0 m³/hr (0.2-0.4 Mpa)
Clean Air Consumption 35 - 80 m³/hr (0.3-0.6 Mpa) 35 - 80 m³/hr (0.3-0.6 Mpa) 35 - 80 m³/hr (0.3-0.6 Mpa)
Exhaust Volume 3500 - 4800 m³/h 3500 - 4800 m³/h 3500 - 4800 m³/h
Weight 9,300 kg 9,300 kg 9,300 kg


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